Wise Therapeutics: Creating a Positive Impact on Global Mental Health Crisis

Wise Therapeutics (now Arcade Therapeutics)

Wise Therapeutics, now operating as Arcade Therapeutics, is a digital therapeutics company combining clinical neuroscience with game design to make mental health support more accessible. It was co-founded by Dr Tracy Dennis-Tiwary, a leading anxiety researcher, and Raj Amin, a digital health entrepreneur. The science behind the work is attention bias modification (ABM), a clinically validated technique for reducing anxiety symptoms.

The challenge: closing the mental health access gap

Around 60 million Americans report mental health symptoms each year, and roughly half never seek treatment. Cost, stigma and limited access to clinicians are the recurring barriers. Wise wanted to test a different route: a mobile-first product, built on validated science, short enough to fit into a real schedule, and engaging enough to actually be opened.

The engagement brief

Wise engaged Tarento as its technology partner to design and build the first product in the pipeline: Personal Zen, a mobile game delivering an ABM micro-intervention in a few minutes a day. The brief covered three things:

• A native, low-friction mobile experience for iOS and Android
• Faithful translation of the clinical ABM exercise into engaging gameplay
• A foundation that could later plug into enterprise and healthcare distribution

What Tarento delivered

Tarento took the science behind Personal Zen into a launched mobile product available on iOS and Android. The collaboration covered product engineering, mobile development and the UX work needed to keep the therapeutic mechanic clinically faithful inside a consumer game. Personal Zen later became available as a wellness benefit for employers, health plans and care providers adding accessible mental health support to their existing offering.

Outcome and what came next

Personal Zen launched into both consumer and employer channels and became the scientific foundation for the company's next generation of prescription digital therapeutic candidates. Wise has since rebranded to Arcade Therapeutics and continues to develop game-based therapeutic products for anxiety and related mental health indications.

Why HealthTech founders choose Tarento

Wise's brief was the test most digital therapeutic founders face: take serious science and ship a consumer-grade product without breaking either. That is how Tarento partners with HealthTech companies, from MVP through to enterprise rollout.